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prenalterol-d7

Names

[ CAS No. ]:
57526-81-5

[ Name ]:
prenalterol-d7

[Synonym ]:
4-({2-hydroxy-3-[(1-methylethyl)amino]propyl}oxy)phenol
Phenol, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-
4-{2-hydroxy-3-[(1-methylethyl)amino]propoxy}phenol
4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenol
4-[2-Hydroxy-3-(isopropylamino)propoxy]phenol

Biological Activity

[Description]:

Prenalterol is a selective β1-adrenergic receptor agonist. Prenalterol has no effect on gut smooth muscle contractile activity. Prenalterol can be used for researching cardiovascular disease[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[Target]

β1 adrenoceptor


[References]

[1]. Seiler R, et al. alpha- and beta-adrenergic receptor mechanisms in spontaneous contractile activity of rat ileal longitudinal smooth muscle. J Gastrointest Surg. 2005;9(2):227-235.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
397.7±32.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H19NO3

[ Molecular Weight ]:
225.28

[ Flash Point ]:
194.3±25.1 °C

[ Exact Mass ]:
225.136490

[ PSA ]:
61.72000

[ LogP ]:
1.04

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.538

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL5090000
CHEMICAL NAME :
Phenol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (S)-
CAS REGISTRY NUMBER :
57526-81-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H19-N-O3
MOLECULAR WEIGHT :
225.32
WISWESSER LINE NOTATION :
QR DO1YQ1NY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
84 mg/kg
SEX/DURATION :
female 15-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 24(2),44A,1981

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds