2,6-Dimethylbromobenzene

Names

[ CAS No. ]:
576-22-7

[ Name ]:
2,6-Dimethylbromobenzene

[Synonym ]:
EINECS 209-397-7
2-Bromo-1,3-dimethylbenzene
2,6-Dimethyl bromobenzene
Benzene, 2-bromo-1,3-dimethyl-
2,6-dimethyl-1-bromobenzene
MFCD00000075
2-Bromo-m-xylene

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
204.4±9.0 °C at 760 mmHg

[ Melting Point ]:
−10 °C(lit.)

[ Molecular Formula ]:
C₈H₉Br

[ Molecular Weight ]:
185.061

[ Flash Point ]:
73.9±0.0 °C

[ Exact Mass ]:
183.988754

[ LogP ]:
3.91

[ Vapour Pressure ]:
0.4±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.544

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY9020000

CHEMICAL NAME :: Benzene, 2-bromo-1,3-dimethyl-

CAS REGISTRY NUMBER :: 576-22-7

BEILSTEIN REFERENCE NO. :: 1929780

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H9-Br

MOLECULAR WEIGHT :: 185.08

WISWESSER LINE NOTATION :: ER B1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07031

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
UN 2810

[ WGK Germany ]:
3

[ RTECS ]:
CY9020000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

A versatile catalyst system for Suzuki-Miyaura syntheses of sterically hindered biaryls employing a cyclobutene-1,2-bis(imidazolium) salt.

Chem. Commun. (Camb.) 46 , 2995-2997, (2010)

The catalyst system consisting of 3,3'-(3,4-bis(dichloro-methylene)cyclobut-1-ene-1,2-diyl)bis(1-methyl-1H-imidazolium) bis(tetrafluoroborate), Pd(OAc)(2) and NaOtBu in toluene proved to be very effec...