Ac-Gly-Ala-Lys(Ac)-AMC

Names

[ Name ]:
Ac-Gly-Ala-Lys(Ac)-AMC

[Synonym ]:
AC-GLY-ALA-LYS(AC)-AMC
Ac-GAK(Ac)-AMC

Biological Activity

[Description]:

Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ptacek J, et, al. Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells. Int J Mol Sci. 2023 Mar 1;24(5):4720.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₃N₅O₇

[ Molecular Weight ]:
515.56

[ Exact Mass ]:
515.23800

[ PSA ]:
175.71000

[ LogP ]:
2.10850

Ac-Gly-Ala-Lys(Ac)-AMC

Names

Biological Activity

Chemical & Physical Properties

Related Compounds