2-Methylanisole

Names

[ CAS No. ]:
578-58-5

[ Name ]:
2-Methylanisole

[Synonym ]:
1-Methoxy-2-methylbenzene
2-Methylanisole
EINECS 209-426-3
MFCD00008373
Methyl 2-methylphenyl ether
Benzene, 1-methoxy-2-methyl-

Biological Activity

[Description]:

2-Methylanisole is a monomethoxybenzene and acts as an intermediate for the preparation of compounds with methylhydroquinone core [1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. James RVyvyan, et al. Total synthesis of (±)-heliannuol D, an allelochemical from Helianthus annuus. Tetrahedron Letters. Volume 41, Issue 8, 19 February 2000

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
171.0±0.0 °C at 760 mmHg

[ Melting Point ]:
170-172 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀O

[ Molecular Weight ]:
122.164

[ Flash Point ]:
51.7±0.0 °C

[ Exact Mass ]:
122.073166

[ PSA ]:
9.23000

[ LogP ]:
2.59

[ Vapour Pressure ]:
1.9±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.494

[ Storage condition ]:
Flammables area

[ Water Solubility ]:
immiscible

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S16

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29093090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Identification of odorants in frankincense (Boswellia sacra Flueck.) by aroma extract dilution analysis and two-dimensional gas chromatography-mass spectrometry/olfactometry.

Phytochemistry 109 , 66-75, (2014)

Frankincense has been known, traded and used throughout the ages for its exceptional aroma properties, and is still commonly used in both secular and religious settings to convey a pleasant odor. Surp...

An assessment of the reaction energetics for cytochrome P450-mediated reactions.

Arch. Biochem. Biophys. 385(1) , 220-30, (2001)

Regioselectivity is used to determine the absolute energetic differences for four different reactions catalyzed by P450. Abstraction of a hydrogen from a benzylic carbon containing a chlorine has a 1....

(+)- and (-)-mutisianthol: first total synthesis, absolute configuration, and antitumor activity.

J. Org. Chem. 74(6) , 2561-6, (2009)

The first synthesis of the natural product (+)-mutisianthol was accomplished in 11 steps and in 21% overall yield from 2-methylanisole. The synthesis of its enantiomer was also performed in a similar ...