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CTPB

Names

[ CAS No. ]:
586976-24-1

[ Name ]:
CTPB

[Synonym ]:
ctpb

Biological Activity

[Description]:

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Histone Acetyltransferase

[Target]

p300


[In Vitro]

CTPB is a synthetic HAT activator, which promotes the transcription by increasing the H3 and H4 acetylation in nucleosome[1].

[References]

[1]. Sivanandam M, et al. Investigation of activation mechanism and conformational stability of N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxybenzamide and N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamidein the active site of p300 histone acetyl transferase enzyme by molecular dynamics and binding free-energy studies. J Biomol Struct Dyn. 2018 Oct 9:1-38.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H43ClF3NO2

[ Molecular Weight ]:
554.12700

[ Exact Mass ]:
553.29300

[ PSA ]:
38.33000

[ LogP ]:
10.71650

[ Storage condition ]:
2-8℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds