CA 1001

Names

[ Name ]:
CA 1001

[Synonym ]:
EINECS 261-449-8
MFCD00042943

Biological Activity

[Description]:

Calcium ionophore I (ETH 1001) is a selective Ca2+ ionophore for biological membranes. Calcium ionophore I can be used in Ca2+-selective microelectrodes that can be used for quantitative intracellular measurements of resting Ca2+-activities and of slowly changing Ca2+-levels[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Others

[References]

[1]. T R Hinds, et al. The effect of ETH 1001 on ion fluxes across red blood cell membranes. Cell Calcium. 1985 Jun;6(3):265-79.

[2]. D Ammann. Ca2+-selective microelectrodes. Cell Calcium. 1985 Apr;6(1-2):39-55.

Chemical & Physical Properties

[ Density]:
1g/cm3

[ Boiling Point ]:
715.1ºC at 760mmHg

[ Molecular Formula ]:
C₃₈H₇₂N₂O₈

[ Molecular Weight ]:
684.98700

[ Flash Point ]:
386.3ºC

[ Exact Mass ]:
684.52900

[ PSA ]:
111.68000

[ LogP ]:
7.64160

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

Design, properties, and applications of neutral ionophores.

Meth. Enzymol. 56 , 439, (1979)

T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo.

J. Immunol. 183 , 5685-93, (2010)

IL-17A and IL-17F regulate granulopoiesis and are produced by memory T cells. Rag1(-/-) recombinase-activating gene-deficient mice cannot produce mature T cells but maintain normal neutrophil counts. ...

Ca2+ transport mediated by a synthetic neutral Ca2+ -ionophore in biological membranes.

Biochim. Biophys. Acta 470 , 437, (1977)

The effect of a synthetic neutral ligand on the Ca2+ permeability of several biological membranes has been investigated. The ligand had been previously shown to possess Ca2+ -ionophoric activities in ...