Sulfaquinoxaline
Names
[ CAS No. ]:
59-40-5
[ Name ]:
Sulfaquinoxaline
[Synonym ]:
sulfaquinoxaline
Benzenesulfonamide, 4-amino-N-2-quinoxalinyl-
Kokozigal
4-Amino-N-[(2E)-2(1H)-quinoxalinylidene]benzenesulfonamide
sulquin
N1-2-quinoxalylsulfanilamide
MFCD00055406
anti-k
EINECS 213-526-2
N1-(2-Quinoxalyl)sulfanilamide
sulfacox
sulphaquinoxaline
italquina
4-Amino-N-(2-quinoxalinyl)benzenesulfonamide
Benzenesulfonamide, 4-amino-N-[(2E)-2(1H)-quinoxalinylidene]-
sulfaline
4-Amino-N-(quinoxalin-2-yl)benzenesulfonamide
Compound 3-120
avicocid
SUQUIN
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Bacterial, Parasite[1][2]
[In Vivo]
[Animal admin]
[References]
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
557.0±52.0 °C at 760 mmHg
[ Melting Point ]:
247-2480C
[ Molecular Formula ]:
C14H12N4O2S
[ Molecular Weight ]:
300.336
[ Flash Point ]:
290.7±30.7 °C
[ Exact Mass ]:
300.068085
[ PSA ]:
106.35000
[ LogP ]:
1.58
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.718
[ Storage condition ]:
Refrigerator
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WP2100000
- CHEMICAL NAME :
- Sulfanilamide, N(sup 1)-2-quinoxalinyl-
- CAS REGISTRY NUMBER :
- 59-40-5
- BEILSTEIN REFERENCE NO. :
- 0290026
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C14-H12-N4-O2-S
- MOLECULAR WEIGHT :
- 300.36
- WISWESSER LINE NOTATION :
- T66 BN ENJ CMSWR DZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1370 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MahWM# Personal Communication from W.M. Mahlburg, Hopkins Agricultural Chemical Co., P.O. Box 7532, Madison, WI 53707, Nov. 16, 1982 Volume(issue)/page/year: 16NOV1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A370,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9100 mg/kg/26W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 82,357,1944
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1400 mg/kg/14D-I
- TOXIC EFFECTS :
- Blood - hemorrhage Related to Chronic Data - death
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 82,357,1944 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1518 No. of Facilities: 615 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 901 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H317-H334
[ Precautionary Statements ]:
P261-P280-P342 + P311
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R42/43
[ Safety Phrases ]:
S22-S36/37-S45
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
WP2100000
[ HS Code ]:
2935009090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2935009090
[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%
Articles
J. Chromatogr. A. 1345 , 17-28, (2014)
A novel, simple and sensitive method was developed for the simultaneous determination of 22 sulfonamides (SAs) in chicken breast muscle by using the dispersive micro-solid-phase extraction (d-μ-SPE) p...
Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography.J. Chromatogr. A. 1360 , 275-87, (2014)
Superficially porous particles (SPP), or core shell particles, which consist of a non-porous silica core surrounded by a thin shell of porous silica, have gained popularity as a solid support for chro...
Multi-residue Determination of Polar Veterinary Drugs in Livestock and Fishery Products by Liquid Chromatography/Tandem Mass Spectrometry.J. AOAC Int. 98(1) , 230-47, (2015)
Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using ...