Atropine sulfate monohydrate

Names

[ Name ]:
Atropine sulfate monohydrate

[Synonym ]:
MFCD00074815
AtropineSulphateGrPuriss
Atropina Solfato
racemic anisodamine
atropine sulphate
atropin sulfate
Atropsiol
AtropineSulfat
TROPINI SULFAS
ATROPINI SULFAS
Atropt
Atropinsulfat
EINECS 200-235-0

Biological Activity

[Description]:

Atropine sulfate monohydrate is a competitive muscarinic acetylcholine receptor antagonist.Target: mAChRAtropine is a naturally occurring tropane alkaloid extracted from deadly nightshade (Atropa belladonna), Jimson weed (Datura stramonium), mandrake (Mandragora officinarum) and other plants of the family Solanaceae. Atropine is a competitive antagonist of the muscarinic acetylcholine receptors (acetylcholine being the main neurotransmitter used by the parasympathetic nervous system). Atropine dilates the pupils, increases heart rate, and reduces salivation and other secretions [1].

[Related Catalog]:

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> GPCR/G Protein >> mAChR

Signaling Pathways >> Neuronal Signaling >> mAChR

Research Areas >> Neurological Disease

Natural Products >> Alkaloid

[References]

[1]. http://en.wikipedia.org/wiki/Atropine

[Related Small Molecules]

Chemical & Physical Properties

[ Boiling Point ]:
429.8ºC at 760mmHg

[ Melting Point ]:
189-192 °C (A)(lit.)

[ Molecular Formula ]:
C₁₇H₂₅NO₇S

[ Molecular Weight ]:
387.45

[ Flash Point ]:
213.7ºC

[ PSA ]:
191.75000

[ LogP ]:
4.10130

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300 + H330

[ Precautionary Statements ]:
P260-P264-P284-P301 + P310-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R26/28;R36/37/38;R43

[ Safety Phrases ]:
S23-S45-S36/37/39-S26-S1

[ RIDADR ]:
UN 1544 6.1/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
CK2455000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
29399900

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29399900

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