Lauric acid-d23

Names

[ Name ]:
Lauric acid-d23

[Synonym ]:
lauric acid-d23
tricosa-C-deuterio-dodecanoic acid
Lauric-d23 acid
perdeuterolauric acid
(H)Dodecanoic acid
MFCD00144567
Dodecanoic-d acid
dodecanoic acid-d23

Biological Activity

[Description]:

Lauric acid-d23 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
296.1±3.0 °C at 760 mmHg

[ Melting Point ]:
44-46ºC(lit.)

[ Molecular Formula ]:
C₁₂HD₂₃O₂

[ Molecular Weight ]:
223.460

[ Flash Point ]:
134.1±11.9 °C

[ Exact Mass ]:
223.321991

[ PSA ]:
37.30000

[ LogP ]:
5.03

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.448

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-28

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Lauric acid-d23

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Precursor & DownStream

Precursor

DownStream

Related Compounds