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3-Hydroxy-8,9-methylenedioxypterocarpene

Names

[ CAS No. ]:
59901-98-3

[ Name ]:
3-Hydroxy-8,9-methylenedioxypterocarpene

[Synonym ]:
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-ol
6H-[1,3]Dioxolo[5,6][1]benzofuro[3,2-c]chromen-3-ol

Biological Activity

[Description]:

Dehydromaackiain is a potent Neurogenin2 (Ngn2) promoter activator. Dehydromaackiain promotes differentiation of neural stem cells into neurons[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

Ngn2[1]


[In Vitro]

Dehydromaackiain (0.5, 1, 2, 5 µM) 在神经干细胞中以剂量依赖性方式表现出高 Ngn2 启动子活性 [1]。

[References]

[1]. Arai MA, et al. Naturally occurring Ngn2 promoter activators from Butea superba. Mol Biosyst. 2013 Oct;9(10):2489-97.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
530.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H10O5

[ Molecular Weight ]:
282.248

[ Flash Point ]:
274.8±30.1 °C

[ Exact Mass ]:
282.052826

[ PSA ]:
61.06000

[ LogP ]:
3.58

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.734

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds