N-(3-Fluoranthyl)maleimide

Names

[ Name ]:
N-(3-Fluoranthyl)maleimide

[Synonym ]:
N-(3-fluoroanthyl)maleimide
1-(Fluoranthen-3-yl)-1H-pyrrole-2,5-dione
MFCD00042618
N-(3-Fluoranthyl)maleimide
EINECS 262-197-1

Biological Activity

[Description]:

N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Y Miyamoto, et al. Interaction between cell-binding domain and extracellular matrix-binding domain of fibronectin determined by fluorescence depolarization. Biochim Biophys Acta. 1988 Apr 14;953(3):306-13

Chemical & Physical Properties

[ Density]:
1.466g/cm3

[ Boiling Point ]:
526.8ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₁NO₂

[ Molecular Weight ]:
297.30700

[ Flash Point ]:
256.1ºC

[ Exact Mass ]:
297.07900

[ PSA ]:
37.38000

[ LogP ]:
3.98160

[ Index of Refraction ]:
1.875

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN 3077 9 / PGIII

[ HS Code ]:
2925190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Inhibitors of CLK protein kinases suppress cell growth and induce apoptosis by modulating pre-mRNA splicing.

PLoS ONE 10(1) , e0116929, (2015)

Accumulating evidence has demonstrated the importance of alternative splicing in various physiological processes, including the development of different diseases. CDC-like kinases (CLKs) and serine-ar...

Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls.

PLoS ONE 9(9) , e108336, (2014)

Mutations in the ABC transporter ABCC6 were recently identified as cause of Pseudoxanthoma elasticum (PXE), a rare genetic disorder characterized by progressive mineralization of elastic fibers. We us...

Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.

J. Clin. Invest. 125(2) , 831-45, (2015)

Expansion of the polyglutamine (polyQ) tract within the androgen receptor (AR) causes neuromuscular degeneration in individuals with spinobulbar muscular atrophy (SBMA). PolyQ AR has diminished transc...