Narcissoside

Names

[ CAS No. ]:
604-80-8

[ Name ]:
Narcissoside

[Synonym ]:
4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-α-D-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-α-D-mannopyranosyl)-β-D-glucopyranoside
Isorhamnetin 3-O-rutinoside
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-one
Narcissoside
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-on
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl-6-O-(6-deoxy-α-D-mannopyranosyl)-β-D-glucopyranoside
6-O-(6-Désoxy-α-D-mannopyranosyl)-β-D-glucopyranoside de 5,7-dihydroxy-2-(4-hydroxy-3-méthoxyphényl)-4-oxo-4H-chromén-3-yle
Narcissin
Isorhamnetin 3-rhamnoglucoside
Narcisin
Isorhamnetin-3-O-Beta-D-rutinoside
5,7-Dihydroxy-2-(4-hydroxy-3-méthoxyphényl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}méthyl)tétrahydro-2H-pyran-2-yl]oxy}-4H-chromén-4-one
Isorhamnetin 3-rutinoside

Biological Activity

[Description]:

Narcissin (Narcissoside), a flavonol glycoside isolated from Morinda citrifolia, exhibits evident scavenging activity against both authentic ONOO- and SIN-1-derived ONOO- with IC50s of 3.5 and 9.6 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Su BN, et al. Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity.J Nat Prod. 2005 Apr;68(4):592-5.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
953.1±65.0 °C at 760 mmHg

[ Melting Point ]:
182-184ºC

[ Molecular Formula ]:
C₂₈H₃₂O₁₆

[ Molecular Weight ]:
624.544

[ Flash Point ]:
312.9±27.8 °C

[ Exact Mass ]:
624.169006

[ PSA ]:
258.43000

[ LogP ]:
1.73

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.728

[ Storage condition ]:
-20℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ2979500

CHEMICAL NAME :: 4H-Benzopyran-4-one, 3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-gluco pyranosyl)oxy)-5,7- dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-

CAS REGISTRY NUMBER :: 604-80-8

LAST UPDATED :: 199806

DATA ITEMS CITED :: 1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DARUEE Dokl Akad Nauk resp. Uzb. Volume(issue)/page/year: (2),41,1992

Safety Information

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29389090

Articles

Morinda citrifolia (Noni) fruit--phytochemistry, pharmacology, safety. Potterat O and Hamburger M.

Planta Med. 73(3) , 191-9, (2007)