norcholic acid

Norcholic acid is a normal minorbile C23 bile acid having four side chain and exsits in human urine and meconium. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine[1].

Research Areas >> Endocrinology

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Norcholic acid (6.4 g/L; p.o.; 24 hours) shows that averaging 40 % of the administered radioactivity is recovered from the feces during the first 24 hours[1]. Norcholic acid can become prominent under certain pathological conditions. Norcholic acid is efficiently absorbed from intestine and quickly excreted into the bile but not into urine[1]. Animal Model: Male Wistar rats (100~150g) Dosage: 6.4 g/L Administration: P.o. Result: Shows that averaging 40 % of the administered radioactivity was recovered from the feces during the first 24 hours.

[1]. Nakatomi F, et al. Intestinal absorption and metabolism of norcholic acid in rats. J Pharmacobiodyn. 1985;8(7):557-563.