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Ferulamide

Names

[ CAS No. ]:
61012-31-5

[ Name ]:
Ferulamide

[Synonym ]:
Ferulic acid amide
4-hydroxy-3-methoxy-cinnamic acid amide
cinnamamide, 4-hydroxy-3-methoxy-
Ferulasaeure-amid
3-(4-Hydroxy-3-methoxyphenyl)acrylamide
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide
Ferulamid
4-Hydroxy-3-methoxy-zimtsaeure-amid
CINNAMAMIDE,4-HYDROXY-3-METHOXY
(2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylamide
4-Oxy-3-methoxy-zimtsaeure-amid
3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide
Ferulic amide
4-HYDROXY-3-METHOXYCINNAMIDE
2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
Ferulamide
feruloylamide
3-(4-Hydroxy-3-methoxyphenyl)-2-propenamide

Biological Activity

[Description]:

Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR
Signaling Pathways >> Neuronal Signaling >> nAChR
Research Areas >> Neurological Disease

[References]

[1]. Fen Xiu, et al. A New Alkaloid From Portulaca oleracea L. And Its Antiacetylcholinesterase Activity. Nat Prod Res. 2019 Sep;33(18):2583-2590.

[2]. Chun-Jen Chen, et al. (2E)-N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide Induces Apoptosis and Cell Cycle Arrest in HL-60 Cells. Anticancer Res. Jan-Feb 2007;27(1A):343-9.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
435.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H11NO3

[ Molecular Weight ]:
193.199

[ Flash Point ]:
217.0±28.7 °C

[ Exact Mass ]:
193.073898

[ PSA ]:
72.55000

[ LogP ]:
0.58

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.624

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Related Compounds