2-Iodoaniline

Names

[ CAS No. ]:
615-43-0

[ Name ]:
2-Iodoaniline

[Synonym ]:
O-AMINOIODOBENZENE
o-Iodoaniline
2-iodophenylamine
Aniline,2-iodo
Benzenamine, 2-iodo-
2-Iodoaniline
2-iodo aniline
2-iodobenzenamine
ortho-iodoaniline
Aniline,o-iodo
2-iodo-aniline
EINECS 210-426-0
Benzenamine,2-iodo
Aniline, o-iodo-
MFCD00007680

Biological Activity

[Description]:

2-Iodoaniline (2-Iodophenylamine) is an aniline derivative, and has potential hepatotoxic and nephrotoxic activity[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vivo]

2-Iodoaniline (1.0 mM/kg, 1.25 mM/kg for 2.5 mL; i.p.; single dose) exhibits hepatotoxic and nephrotoxic potential in Male Fischer 344 rats[1]. Animal Model: Male Fischer 344 rats (185-260 g)[1] Dosage: 1.0 mM/kg, 1.25 mM/kg for 2.5 mL Administration: Intraperitoneal injection; single dose; monitored renal and hepatic function 24 h after treatment Result: Induced oliguria, diminished kidney weight, tubular casts and decreased renal cortical slice accumulation of organic anions. Elevated plasma ALT/GPT activity and altered morphology in the centrilobular region.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
262.0±23.0 °C at 760 mmHg

[ Melting Point ]:
55-58 °C(lit.)

[ Molecular Formula ]:
C₆H₆IN

[ Molecular Weight ]:
219.023

[ Flash Point ]:
112.3±22.6 °C

[ Exact Mass ]:
218.954483

[ PSA ]:
26.02000

[ LogP ]:
2.30

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.688

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H332-H335

[ Precautionary Statements ]:
P261-P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S36/37-S36/37/39-S26

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
29214210

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%