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IKK-IN-4

Names

[ CAS No. ]:
615529-94-7

[ Name ]:
IKK-IN-4

Biological Activity

[Description]:

IKK-IN-4 is a potent and selective IkappaB kinase 2 (IKKβ orIKK2) inhibitor, with IC50s of 45 and 650 nM for IKKβ and IKKα, respectively[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> IKK
Research Areas >> Inflammation/Immunology

[References]

[1]. Belema M, et al. Synthesis and structure-activity relationship of imidazo(1,2-a)thieno(3,2-e)pyrazines as IKK-beta inhibitors. Bioorg Med Chem Lett. 2007;17(15):4284‐4289.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H19N5S

[ Molecular Weight ]:
337.44

Related Compounds