H-DL-Nle-OH

Names

[ CAS No. ]:
616-06-8

[ Name ]:
H-DL-Nle-OH

[Synonym ]:
Norleucine
NLE
(±)-Norleucine
DL-2-Aminohexanoic Acid
Aminohexanoic acid
2-Aminohexanoic acid,dl
AHX
DL-a-Aminocaproic acid
Dl-α-amino-n-caproic acid
2-aminohexanoic acid
Norleucine,L
2-Aminohexanoic acid, dl-
e-Aminohexanoic acid
UNII:5C81BE5GKK
e-Amino-n-hexanoic acid
DL-α-Aminocaproic acid
e-Norleucine
h-dl-nle-oh
Norleucine, DL-
DL-Norleucine
Norleucine,DL
EINECS 210-462-7
(DL)-2-amino-1-hexanoic acid
2-amino-hexanoic acid
MFCD00064422
(±)-2-Aminohexanoic acid
2-Aminocaproic acid

Biological Activity

[Description]:

H-DL-Nle-OH is a leucine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
234.0±23.0 °C at 760 mmHg

[ Melting Point ]:
>300 °C(lit.)

[ Molecular Formula ]:
C₆H₁₃NO₂

[ Molecular Weight ]:
131.173

[ Flash Point ]:
95.3±22.6 °C

[ Exact Mass ]:
131.094635

[ PSA ]:
63.32000

[ LogP ]:
0.92

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.465

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
11.49 g/L (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Teicoplanin bonded sub-2 μm superficially porous particles for enantioseparation of native amino acids.

J. Pharm. Biomed. Anal. 114 , 247-53, (2015)

Superficially porous particles (SPPs) demonstrate superior efficiency than totally porous particles in chiral separations. In order to obtain high efficiency and fast separation, sub-2 μm SPPs with hi...

Dual-phase osteogenic and vasculogenic engineered tissue for bone formation.

Tissue Eng. Part A 21(3-4) , 530-40, (2015)

Minimally invasive, injectable bone tissue engineering therapies offer the potential to facilitate orthopedic repair procedures, including in indications where enhanced bone regeneration is needed for...

Role of autocleavage in the function of a type III secretion specificity switch protein in Salmonella enterica serovar Typhimurium.

MBio 6 , e01459-15, (2015)

Type III secretion systems (T3SSs) are multiprotein machines employed by many Gram-negative bacteria to inject bacterial effector proteins into eukaryotic host cells to promote bacterial survival and ...