Diethylformamide

Names

[ CAS No. ]:
617-84-5

[ Name ]:
Diethylformamide

[Synonym ]:
Diethylformamide
N,N-Diethylformamide
Formamide, N,N-diethyl-
EINECS 210-533-2
MFCD00003287

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
177.5±0.0 °C at 760 mmHg

[ Melting Point ]:
176-177°C

[ Molecular Formula ]:
C₅H₁₁NO

[ Molecular Weight ]:
101.147

[ Flash Point ]:
60.6±0.0 °C

[ Exact Mass ]:
101.084061

[ PSA ]:
20.31000

[ LogP ]:
0.05

[ Vapour Pressure ]:
1.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.418

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LQ1925000

CHEMICAL NAME :: Formamide, N,N-diethyl-

CAS REGISTRY NUMBER :: 617-84-5

BEILSTEIN REFERENCE NO. :: 1209392

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H11-N-O

MOLECULAR WEIGHT :: 101.17

WISWESSER LINE NOTATION :: VHN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1740 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 85,72,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1740 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,330,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 26,409,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6943 No. of Facilities: 49 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 6718 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
1

[ RTECS ]:
LQ1925000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Fabrication of porous cubic architecture of ZnO using Zn-terephthalate MOFs with characteristic microstructures.

Inorg. Chem. 52(24) , 14028-33, (2013)

A method for synthesizing porous cubic-shaped ZnO particles a few tens of micrometers in size is described on the basis of a pyrolytic conversion of Zn-terephthalate metal-organic frameworks (MOFs). M...

A new and facile synthesis of quinazoline-2,4(1H,3H)-diones.

Org. Lett. 11(6) , 1193-6, (2009)

A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl(2) (0.5...

Metal-catalyzed reduction of HCONR'2, R' = Me (DMF), Et (DEF), by silanes to produce R'2NMe and disiloxanes: a mechanism unraveled.

J. Am. Chem. Soc. 134(2) , 848-51, (2012)

We demonstrate that using Mo(CO)(6), Mo(CO)(5)NMe(3), and (η(5)-C(5)H(5))Mn(CO)(3) as catalysts for the silane, R(3)SiH, reduction of N,N-dimethylformamide (DMF), and N,N-diethylformamide (DEF), we ca...