4-(Dimethylamino)phenol

Names

[ CAS No. ]:
619-60-3

[ Name ]:
4-(Dimethylamino)phenol

[Synonym ]:
4-Dimethylaminophenol
N,N-Dimethyl-p-hydroxyaniline
4-(Dimethylamino)phenol HCl
4-(Dimethylamino)phenol
N,N-Dimethyl-4-aminophenol
DMAP (antidote)
Phenol, 4-(dimethylamino)-
4-(N,N-dimethylamino)phenol
Phenol,4-(dimethylamino)
p-Hydroxy-N,N-dimethylaniline
4-hydroxy N,N-dimethylaniline
p-dimethylaminophenol
Phenol,p-(dimethylamino)

Biological Activity

[Description]:

4-(Dimethylamino)phenol increases the extracellular lactate dehydrogenase (LDH) without markedly affecting gluconeogenesis. 4-(Dimethylamino)phenol cannot decreases the ATP content until the membrane becomes permeable to LDH[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Szinicz LL, et al. Effects of 4-dimethylaminophenol in rat kidneys, isolated rat kidney tubules and hepatocytes. Xenobiotica. 1980;10(7-8):611-620.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
259.7±23.0 °C at 760 mmHg

[ Melting Point ]:
74-76ºC

[ Molecular Formula ]:
C₈H₁₁NO

[ Molecular Weight ]:
137.179

[ Flash Point ]:
135.6±21.3 °C

[ Exact Mass ]:
137.084061

[ PSA ]:
23.47000

[ LogP ]:
1.50

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.590

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%