Glycine ethyl ester hydrochloride

Names

[ CAS No. ]:
623-33-6

[ Name ]:
Glycine ethyl ester hydrochloride

[Synonym ]:
Glycine ethyl ester hydrochloride
Ethyl glycinate hydrochloride
MFCD00012871
ethyl 2-aminoacetate,hydrochloride
EINECS 210-787-4
H-Gly-OEt.HCl
H-Gly-OEt·HCl

Biological Activity

[Description]:

Glycine ethyl ester monohydrochloride is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1 g/cm3

[ Boiling Point ]:
109.5ºC at 760 mmHg

[ Melting Point ]:
145-146 °C(lit.)

[ Molecular Formula ]:
C₄H₁₀ClNO₂

[ Molecular Weight ]:
154.595

[ Exact Mass ]:
154.050903

[ PSA ]:
52.32000

[ LogP ]:
1.01050

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
>1000 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MC0525000

CHEMICAL NAME :: Glycine, ethyl ester, hydrochloride

CAS REGISTRY NUMBER :: 623-33-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H9-N-O2.Cl-H

MOLECULAR WEIGHT :: 139.60

WISWESSER LINE NOTATION :: Z1VO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;Xi: Irritant;

[ Risk Phrases ]:
R41

[ Safety Phrases ]:
S26-S39-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MC0525000

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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