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Zabofloxacin hydrochloride

Names

[ CAS No. ]:
623574-00-5

[ Name ]:
Zabofloxacin hydrochloride

[Synonym ]:
1,8-Naphthyridine-3-carboxylic acid,1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-(methoxyimino)-2,6-diazaspiro(3.4)oct-6-yl)-4-oxo-,hydrochloride (1:1)
DW-224a
Zabofloxacin hydrochloride
1,8-Naphthyridine-3-carboxylic acid,1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-(methoxyimino)-2,6-diazaspiro(3.4)oct-6-yl)-4-oxo-,monohydrochloride
Zabofloxacin monohydrochloride
UNII-O889MR47PQ

Biological Activity

[Description]:

Zabofloxacin hydrochloride (DW-224a) is a novel fluoronaphthyridone quinolone that is considered a potent antibacterial candidate for clinical trials.Zabofloxacin hydrochloride (DW-224a) has excellent activity against gram-positive pathogens including Steptococcus aureus (S. aureus), Streptococcus pyogenes (S. pyrigenes), and S. pneumonia.Zabofloxacin hydrochloride (DW-224a) is considered as an alternative candidate for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP)[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Park HS, et al. Antimicrobial Activity of Zabofloxacin against Clinically Isolated Streptococcus pneumoniae. Molecules. 2016 Nov 17;21(11). pii: E1562.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H21ClFN5O4

[ Molecular Weight ]:
437.85300

[ Exact Mass ]:
437.12700

[ PSA ]:
109.05000

[ LogP ]:
2.17650

Related Compounds