4-Hydroxypyridine

Names

[ CAS No. ]:
626-64-2

[ Name ]:
4-Hydroxypyridine

[Synonym ]:
4HPY
MFCD00006419
4-oxypyridine
4-Hydroxypyride
4-Hydroxypyridine
pyridin-4-one
pyridin-4-ol
4-(1H)-Pyridone, , pract
Pyridin-4(1H)-one
Hydroxypyridinoxid
4(1H)-pyridinone
pyrid-4-one
1,4-DIHYDRO-4-PYRIDINONE
1H-Pyridin-4-ol
G-PYRIDONE
4HYDROXYPRIDINE
4(1H)-pyridone
4-hydroxy-pyridine
4-HDROXYPYRIDINE
4-hydroxypyridone
EINECS 210-958-3
4-(1H)-PYRIDONE
4-PYRIDINONE
Hydroxypyridine,4
4-oxo-1,4-dihydropyridine
4-PYRIDOL
4-pyridone
p-hydroxy pyridine
4-Pyridinol
1,4-DIHYDRO-4-PYRIDINONE FOR SYNTHESIS

Biological Activity

[Description]:

Pyridin-4-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
380.6±0.0 °C at 760 mmHg

[ Melting Point ]:
150-151 °C(lit.)

[ Molecular Formula ]:
C₅H₅NO

[ Molecular Weight ]:
95.10

[ Flash Point ]:
182.3±20.4 °C

[ Exact Mass ]:
95.037117

[ PSA ]:
33.12000

[ LogP ]:
-1.30

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.560

[ Water Solubility ]:
Soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU7701450

CHEMICAL NAME :: 4-Pyridinol

CAS REGISTRY NUMBER :: 626-64-2

BEILSTEIN REFERENCE NO. :: 0105800

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C5-H5-N-O

MOLECULAR WEIGHT :: 95.11

WISWESSER LINE NOTATION :: T6NJ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 923 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 23,815,1985

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
UU7701450

[ HS Code ]:
2933399090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

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Biochemistry 45(31) , 9575-83, (2006)

Tyrosine phenol-lyase (TPL) from Citrobacter freundii is a pyridoxal 5'-phosphate (PLP)-dependent enzyme that catalyzes the reversible hydrolytic cleavage of l-Tyr to give phenol and ammonium pyruvate...

Discovery of γ-secretase modulators with a novel activity profile by text-based virtual screening.

ACS Chem. Biol. 7(9) , 1488-95, (2012)

We present an integrated approach to identify and optimize a novel class of γ-secretase modulators (GSMs) with a unique pharmacological profile. Our strategy included (i) virtual screening through app...

Characterization of subdomain IIA binding site of human serum albumin in its native, unfolded, and refolded states using small molecular probes.

J. Am. Chem. Soc. 130(32) , 10793-801, (2008)

Subdomain IIA binding site of human serum albumin (HSA) was characterized by examining the change in HSA fluorescence in the native, unfolded, and refolded states. The study was carried out in the abs...