Methyl 4-Fluorobenzoylacetate

Names

[ Name ]:
Methyl 4-Fluorobenzoylacetate

[Synonym ]:
Benzenepropanoic acid, 4-fluoro-β-oxo-, methyl ester
EINECS 263-889-6
methyl p-fluorobenzoylacetate
Methyl 3-(4-fluorophenyl)-3-oxopropanoate
MFCD00000355

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
263.5±15.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₉FO₃

[ Molecular Weight ]:
196.175

[ Flash Point ]:
109.8±15.3 °C

[ Exact Mass ]:
196.053574

[ PSA ]:
43.37000

[ LogP ]:
1.39

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.497

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Substituted coumarins as potent 5-lipoxygenase inhibitors.

Bioorg. Med. Chem. Lett. 16(9) , 2528-31, (2006)

Leukotriene biosynthesis inhibitors have potential as therapeutic agents for asthma and inflammatory diseases. A novel series of substituted coumarin derivatives has been synthesized and the structure...

One-pot synthesis of 3-amino-4-aryl-and 3-amino-4-hetarylfurazans. Sheremetev AB.

Russ. Chem. Bull. 54(4) , 1057-59, (2005)