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IMB-301

Names

[ CAS No. ]:
64009-84-3

[ Name ]:
IMB-301

[Synonym ]:
3-(2,4-Dichlorophenyl)-4-(1H-imidazol-1-yl)butyl 4-fluorophenyl ether
1H-Imidazole,1-[2-(2,4-dichlorophenyl)-4-(4-fluorophenoxy)butyl]
IMB-301

Biological Activity

[Description]:

IMB-301 is a HIV-1 auxilins Vif degradation hA3G antagonist. IMB-301 inhibits hA3G-Vif interactions to inhibit Vif degradations hA3G. IMB-301 has anti-HIV-1 activity[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[In Vitro]

IMB-301 can effectively inhibit the combination of Vif and hA3G[1]. IMB 301 can be by inhibiting Vif to inhibit Vif degradations hA3G with hA3G binding specificities[1].

[References]

[1]. Zhou, Jinming, et al. Applications of the IMB-301 in antiviral drugs is prepared. CN108261413A.

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Boiling Point ]:
548.1ºC at 760mmHg

[ Molecular Formula ]:
C19H17Cl2FN2O

[ Molecular Weight ]:
379.25500

[ Flash Point ]:
285.3ºC

[ Exact Mass ]:
378.07000

[ PSA ]:
27.05000

[ LogP ]:
5.58190

[ Index of Refraction ]:
1.589

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds