Nuclear Fast Red

Names

[ Name ]:
Nuclear Fast Red

[Synonym ]:
Kernechtrot NFR
CALCIUM RED
KERNECHTROT
2-Anthracenesulfonic acid, 4-amino-9,10-dihydro-1,3-dihydroxy-9,10-dioxo-, monosodium salt
Sodium 4-amino-1,3-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
FAST RED B
Calcin red
EINECS 229-088-0
NFR
2-Anthracenesulfonic acid, 4-amino-9,10-dihydro-1,3-dihydroxy-9,10-dioxo-, sodium salt (1:1)
nuclear
MFCD00078493
Sodium 4-amino-1,3-dihydroxy-9,10-dioxo-9,10-dihydro-2-anthracenesulfonate

Biological Activity

[Description]:

Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium[1]. Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine[2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Yi Cui, et al. Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine. Talanta. 2014 Dec;130:536-41.

[2]. M Frank , et al. Certification procedures for nuclear fast red (Kernechtrot), CI 60760. Biotech Histochem. 2007 Feb;82(1):35-9.

Chemical & Physical Properties

[ Melting Point ]:
300 °C

[ Molecular Formula ]:
C₁₄H₈NNaO₇S

[ Molecular Weight ]:
357.271

[ Exact Mass ]:
356.991913

[ PSA ]:
166.20000

[ LogP ]:
2.02150

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

White matter tracts for the trafficking of neural progenitor cells characterized by cellular MRI and immunohistology: the role of CXCL12/CXCR4 signaling.

Brain Struct. Funct. , (2014)

White matter tracts are important for the trafficking of neural progenitor cells (NPCs) in both normal and pathological conditions, but the underlying mechanism is not clear. The directionality of whi...

IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease.

J. Clin. Invest. 125 , 3198-214, (2015)

Macrophages (Mø) are integral in ischemia/reperfusion injury-incited (I/R-incited) acute kidney injury (AKI) that leads to fibrosis and chronic kidney disease (CKD). IL-34 and CSF-1 share a receptor (...

Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse.

PLoS ONE 9(6) , e98444, (2014)

Intervertebral discs (IVDs) are strong fibrocartilaginous joints that connect adjacent vertebrae of the spine. As discs age they become prone to failure, with neurological consequences that are often ...