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(Deamino-Pen1,Val4,D-Arg8)-Vasopressin

Names

[ CAS No. ]:
64158-84-5

[ Name ]:
(Deamino-Pen1,Val4,D-Arg8)-Vasopressin

[Synonym ]:
DEAMINO-PEN-TYR-PHE-VAL-ASN-CYS-PRO-DARG-GLY-NH2
1-Deaminopenicillamine-4-val-argipressin
3-MERCAPTO-3-METHYL-BUTYRYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2
(DEAMINO-PEN1,VAL4,D-ARG8)-VASOPRESSIN
deaminopenicillamine(1)-val(4)-argipressi
3-Mercapto-3-methyl-butyryl-Tyr-Phe-Val-Asn-Cys-Pro-D-Arg-Gly-NH2 (Disulfide bond)
argipressin,deaminopenicillamine(1)-Val(4)

Biological Activity

[Description]:

[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A) is an arginine-vasopressin (AVP) antagonist. AVP-A can significantly lower plasma aldosterone concentration in rats. AVP-A can be used for the research of the growth and steroidogenic capacity of rat adrenal zona glomerulosa[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor
Research Areas >> Metabolic Disease

[References]

[1]. Mazzocchi G, et al. Evidence that endogenous arginine-vasopressin (AVP) is involved in the maintenance of the growth and steroidogenic capacity of rat adrenal zona glomerulosa. J Steroid Biochem Mol Biol. 1993 Apr;45(4):251-6.  

Chemical & Physical Properties

[ Density]:
1.47g/cm3

[ Molecular Formula ]:
C48H69N13O11S2

[ Molecular Weight ]:
1068.27000

[ Exact Mass ]:
1067.47000

[ PSA ]:
442.92000

[ LogP ]:
2.99230

[ Index of Refraction ]:
1.682

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20

[ Safety Phrases ]:
36

Related Compounds