BIS-TRIS PROPANE

Names

[ Name ]:
BIS-TRIS PROPANE

[Synonym ]:
2,2'-(Propane-1,3-diyldiimino)bis[2-(hydroxymethyl)propane-1,3-diol]
2,2'-(Propan-1,3-diyldiimino)bis[2-(hydroxymethyl)propan-1,3-diol]
BIS-Tris Propane,ULTROL Grade
Bistrishydroxymethylmethylaminopropane
BIS-TRIS PROPANE SIGMAULTRA
BIS-TRISPROPANE,BIOLOGICALBUFFER
BIS-TRIS PROPANE
2,2'-(1,3-Propanediyldiimino)bis[2-(hydroxymethyl)-1,3-propanediol]
1,3-Propanediol, 2,2'-(1,3-propanediyldiimino)bis[2-(hydroxymethyl)-
1,3-Bis[tris(hydroxymethyl)methylamino]propane
MFCD00004689
2,2'-(Propane-1,3-diyldiimino)bis(2-(hydroxymethyl)propane-1,3-diol)
1,3-Propanediol, 2,2'-(1,3-propanediyldiimino)bis(2-(hydroxymethyl)-
EINECS 264-899-3

Biological Activity

[Description]:

Bis-tris propane (BTP) is a water-soluble buffer substance. Bis-tris propane can be used as a suitable buffer for polymerase chain reaction (PCR). Bis-tris propane can enhance the stability or activity of restriction enzymes[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. K A Eckert, et al. DNA polymerase fidelity and the polymerase chain reaction. PCR Methods Appl. 1991 Aug;1(1):17-24.

[2]. J R Wenner, et al. Buffer effects on EcoRV kinetics as measured by fluorescent staining and digital imaging of plasmid cleavage. Anal Biochem.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
573.3±50.0 °C at 760 mmHg

[ Melting Point ]:
164-165 °C(lit.)

[ Molecular Formula ]:
C₁₁H₂₆N₂O₆

[ Molecular Weight ]:
282.334

[ Flash Point ]:
224.5±20.7 °C

[ Exact Mass ]:
282.179077

[ PSA ]:
145.44000

[ LogP ]:
-1.89

[ Vapour Pressure ]:
0.0±3.6 mmHg at 25°C

[ Index of Refraction ]:
1.565

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
H2O: 1 M at 20 °C, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S22-S24/25-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29221980

Articles

Induction of Neuron-Specific Degradation of Coenzyme A Models Pantothenate Kinase-Associated Neurodegeneration by Reducing Motor Coordination in Mice.

PLoS ONE 10 , e0130013, (2015)

Pantothenate kinase-associated neurodegeneration, PKAN, is an inherited disorder characterized by progressive impairment in motor coordination and caused by mutations in PANK2, a human gene that encod...

Phosphate modulates receptor sulfotyrosine recognition by the chemokine monocyte chemoattractant protein-1 (MCP-1/CCL2).

Org. Biomol. Chem. 13(7) , 2162-9, (2015)

Tyrosine sulfation is a widespread post-translational modification that mediates the interactions of secreted and membrane-associated proteins in such varied biological processes as peptide hormone ac...

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.

J. Med. Chem. 58 , 5649-73, (2015)

Overexpression of ATAD2 (ATPase family, AAA domain containing 2) has been linked to disease severity and progression in a wide range of cancers, and is implicated in the regulation of several drivers ...