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PTP1B-IN-13

Names

[ CAS No. ]:
650621-20-8

[ Name ]:
PTP1B-IN-13

[Synonym ]:
Benzenepropanamide, N-[[[4-[[(3,4-dimethylphenyl)amino]sulfonyl]phenyl]amino]thioxomethyl]-
MFCD04104932
N-({4-[(3,4-Dimethylphenyl)sulfamoyl]phenyl}carbamothioyl)-3-phenylpropanamide
PTP1B-IN-13

Biological Activity

[Description]:

PTP1B-IN-13 is a selective PTP1B inhibitor targeting the allosteric site with an IC50 value of 1.59 μM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
Research Areas >> Others

[References]

[1]. Yang Y, et al. Integrated Approach to Identify Selective PTP1B Inhibitors Targeting the Allosteric Site. J Chem Inf Model. 2021 Sep 27;61(9):4720-4732.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C24H25N3O3S2

[ Molecular Weight ]:
467.60

[ Exact Mass ]:
467.133728

[ LogP ]:
5.24

[ Index of Refraction ]:
1.667

Related Compounds