Ibuprofen Impurity F

Names

[ Name ]:
Ibuprofen Impurity F

[Synonym ]:
3-[4-(2-methylpropyl)phenyl]propanoic acid
Ibuprofen Impurity 6

Biological Activity

[Description]:

Ibuprofen Impurity F is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

Chemical & Physical Properties

[ Density]:
1.034 g/cm3

[ Boiling Point ]:
327.445ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₈O₂

[ Molecular Weight ]:
206.28100

[ Flash Point ]:
224.48ºC

[ Exact Mass ]:
206.13100

[ PSA ]:
37.30000

[ LogP ]:
2.90230

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2916399090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%