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Glochidone

Names

[ CAS No. ]:
6610-55-5

[ Name ]:
Glochidone

[Synonym ]:
Betuline
TROCHOL
betula camphor
BETULOL
BETULINOL
betulinic alcohol
Lupa-1,20(29)-dien-3-one
Glochidone

Biological Activity

[Description]:

Glochidone is an anti-cancer agent with IC50s of 5.52 μM and 7.84 μM against HOP-62 and EPLC-272H cells, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Chen H, et al. Glochidiol, a natural triterpenoid, exerts its anti-cancer effects by targeting the colchicine binding site of tubulin. Invest New Drugs. 2021 Apr;39(2):578-586.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
489.8±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H46O

[ Molecular Weight ]:
422.69

[ Flash Point ]:
258.1±14.0 °C

[ Exact Mass ]:
422.354858

[ PSA ]:
17.07000

[ LogP ]:
10.09

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.517

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream


Related Compounds