Tsugafolin

Names

[ Name ]:
Tsugafolin

[Synonym ]:
7-Hydroxy-5-methoxy-2-(4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-5-methoxy-2-(4-methoxyphenyl)-
Tsugafolin
7-Hydroxy-5,4'-dimethoxyflavanone

Biological Activity

[Description]:

Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC50=118 μM) and devoid cytotoxicity (<150 μM). Tsugafolin can be isolated from Vitex leptobotrys[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[References]

[1]. Tanaka R, et al. A new flavanone derivative from the leaves of Tsuga diversifolia[J]. Planta medica, 1989, 55(06): 570-571.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
524.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₆O₅

[ Molecular Weight ]:
300.31

[ Flash Point ]:
196.0±23.6 °C

[ Exact Mass ]:
300.099762

[ PSA ]:
64.99000

[ LogP ]:
3.62

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.597

Safety Information

[ Hazard Codes ]:
Xi

Tsugafolin

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds