(S)-ketorolac

Names

[ Name ]:
(S)-ketorolac

[Synonym ]:
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-
Ketorolac
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(S)-Ketorolac
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
UNII:YZI5105V0L
Ketorolac Impurity 2

Biological Activity

[Description]:

(S)-Ketorolac is a nonsteroidal anti-inflammatory agent. (S)-ketorolac exhibits potent COX1 and COX2 enzyme inhibition[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[Target]

COX1, COX2[1]

[References]

[1]. Handley DA, et al. Preclinical enantioselective pharmacology of (R)- and (S)-ketorolac. J Clin Pharmacol. 1998 Feb;38(2S):25S-35S.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
493.2±40.0 °C at 760 mmHg

[ Melting Point ]:
160-167?C

[ Molecular Formula ]:
C₁₅H₁₃NO₃

[ Molecular Weight ]:
255.269

[ Flash Point ]:
252.1±27.3 °C

[ Exact Mass ]:
255.089539

[ PSA ]:
59.30000

[ LogP ]:
2.08

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.659

[ Storage condition ]:
Refrigerator

(S)-ketorolac

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds