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DL-3-Methylaspartic acid

Names

[ CAS No. ]:
6667-60-3

[ Name ]:
DL-3-Methylaspartic acid

[Synonym ]:
Dl-aspartic acid,3-methyl
threo-3-methylaspartic acid
(+-)-threo-2-amino-3-methyl-succinic acid
DL-3-Methylaspartic acid
DL-3-Me-Asp-OH
3-METHYL-ASPARTIC ACID
3-Methylaspartic acid
2-AMINO-3-METHYLSUCCINIC ACID
Aspartic acid, 3-methyl-
(+-)-threo-3-Amino-2-methyl-bernsteinsaeure
(+-)-threo-2-Amino-3-methyl-bernsteinsaeure

Biological Activity

[Description]:

2-Amino-3-methylsuccinic acid is an aspartic acid derivative[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
259.2±30.0 °C at 760 mmHg

[ Melting Point ]:
270-276ºC

[ Molecular Formula ]:
C5H9NO4

[ Molecular Weight ]:
147.129

[ Flash Point ]:
110.6±24.6 °C

[ Exact Mass ]:
147.053162

[ PSA ]:
100.62000

[ LogP ]:
-0.32

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.519

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Electronic structure studies of the adenosylcobalamin cofactor in glutamate mutase.

Biochemistry 44 , 15167-15181, (2005)

Glutamate mutase (GM) is a cobalamin-dependent enzyme that catalyzes the reversible interconversion of L-glutamate and L-threo-3-methylaspartate via a radical-based mechanism. To initiate catalysis, t...

Interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate: a distinctive B(12)-dependent carbon-skeleton rearrangement.

J. Am. Chem. Soc. 123(33) , 7963-72, (2001)

The interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate catalyzed by B(12)-dependent glutamate mutase is discussed using results from high-level ab initio molecular orbital calculations. Ev...

[Oxidative deamination of beta-methylaspartic acid].

Boll. Soc. Ital. Biol. Sper. 55(12) , 1189-95, (1979)

beta-methyl-aspartic acid is a substrate for beef kidney D-aspartate oxidase. The first product of a typical oxidative deamination, undergoes further spontaneous process of decarboxylation which gives...


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Related Compounds