2-(BOC-Amino)ethanethiol

Names

[ Name ]:
2-(BOC-Amino)ethanethiol

[Synonym ]:
tert-butyl N-(2-sulfanylethyl)carbamate

Biological Activity

[Description]:

2-(Boc-amino)ethanethiol (compound 35) is a bifunctional cross-linker that can be used in the synthesis of bifunctional azobenzene glycoconjugates[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Anne Müller, et al. Synthesis of Bifunctional Azobenzene Glycoconjugates for Cysteine-Based Photosensitive Cross-Linking with Bioactive Peptides. Chemistry. 2015 Sep 21;21(39):13723-31.

Chemical & Physical Properties

[ Density]:
1.049 g/mL at 20ºC(lit.)

[ Boiling Point ]:
68ºC0.3 mm Hg(lit.)

[ Molecular Formula ]:
C₇H₁₅NO₂S

[ Molecular Weight ]:
177.26

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
177.08200

[ PSA ]:
77.13000

[ LogP ]:
1.83180

[ Appearance of Characters ]:
Viscous Liquid or Low Melting Solid | Clear colorless to yellow

[ Index of Refraction ]:
n20/D 1.474(lit.)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Synthesis of Bifunctional Azobenzene Glycoconjugates for Cysteine-Based Photosensitive Cross-Linking with Bioactive Peptides.

Chemistry 21 , 13723-31, (2015)

Azobenzene linker molecules can be utilized to control peptide/protein function when they are ligated to appropriately spaced amino acid side chains of the peptide. This is because the photochemical E...

Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors.

Lab Chip 15 , 2162-72, (2015)

A novel, rapid and simple method for the preparation of emulsion-templated monoliths in microfluidic channels based on thiol-ene chemistry is presented. The method allows monolith synthesis and anchor...

A convenient route to thiol terminated peptides for conjugation and surface functionalization strategies.

Bioconjug. Chem. 6 , 323, (1995)

The derivatization of poly(p-(chloromethyl)styrene-co-divinylbenzene) (Merrifield resin) with N-(tert-butoxycarbonyl)-2-aminoethanethiol is presented as a convenient route for the generation of thiol ...