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Antidepressant agent 1

Names

[ CAS No. ]:
67411-41-0

[ Name ]:
Antidepressant agent 1

Biological Activity

[Description]:

Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. Antidepressant agent 1 also can be used to increase body temperature[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[In Vitro]

Antidepressant agent 1 (compound I) is prepared in 56% yields by reduction of compound II by NaBH4-AcOH. Compound II is obtained by condensation of compound III with BrCH2CH(OBu)2 followed by acid-catalyzed cyclization[1].

[References]

[1]. V. I. Shvedov, et al. Synthesis and properties of new analogs of pyrazidole-halogeno-derivatives of 1,10-trimethylene-2-ethyl-1,2,3,4-tetrahydropyrazino [1,2-a]indole. Pharmaceutical Chemistry Journal volume 12, pages633-635(1978).

Chemical & Physical Properties

[ Molecular Formula ]:
C16H19BrN2

[ Molecular Weight ]:
319.24

Related Compounds