TAPSO

Names

[ Name ]:
TAPSO

[Synonym ]:
3-[(1,3-Dihydroxy-2-propanyl)(hydroxymethyl)amino]-2-hydroxy-1-propanesulfonic acid
TAPSO
3,3-dibromo-tetrahydro-pyran-2-ol
3,3-Dibrom-2-hydroxytetrahydropyran
MFCD00038352
1-Propanesulfonic acid, 2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-
3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}-2-hydroxypropane-1-sulfonic acid
UNII:45Q4J0071U
2-Hydroxy-3-{[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino}propane-1-sulfonic acid
2-Hydroxy-3.3-dibrom-tetrahydro-pyran
TAPSO (buffer)
3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropane-sulfonic acid
EINECS 269-993-8
1-Propanesulfonic acid, 2-hydroxy-3-[[2-hydroxy-1-(hydroxymethyl)ethyl](hydroxymethyl)amino]-
3-{[1,3-Dihydroxy-2-(hydroxymethyl)-2-propanyl]amino}-2-hydroxy-1-propanesulfonic acid

Biological Activity

[Description]:

TAPSO is a common biological buffer, a pH stabilization reagent, with effective pH ranging from 7-8, and pKa values ranging from 7.5–9.0. TAPSO contains Tris groups and exhibits quite reactive activity with zwitterionic glycine peptides[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Machado CM, et al. Interpretation of non-Nernstian slopes in graphic analysis of data collected in pH range close to deprotonation of a ligand Part I. A glass electrode potentiometric and polarographic study of Cd-(TAPSO)x-(OH)y and Zn-(TAPSO)x-(OH)y systems. Talanta. 2006 Jan 15;68(3):819-30.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Melting Point ]:
224-229 °C (dec.)

[ Molecular Formula ]:
C₇H₁₇NO₇S

[ Molecular Weight ]:
259.277

[ Exact Mass ]:
259.072571

[ PSA ]:
155.70000

[ LogP ]:
-2.64

[ Index of Refraction ]:
1.598

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922199090

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%