2,4-Imidazolidinedione,5-methyl-5-phenyl-

Names

[ CAS No. ]:
6843-49-8

[ Name ]:
2,4-Imidazolidinedione,5-methyl-5-phenyl-

[Synonym ]:
5-methyl-5-phenylhydantoin
MFCD00005265
EINECS 229-928-6

Chemical & Physical Properties

[ Density]:
1.138g/cm3

[ Melting Point ]:
199-201ºC(lit.)

[ Molecular Formula ]:
C₁₀H₁₀N₂O₂

[ Molecular Weight ]:
190.19900

[ Exact Mass ]:
190.07400

[ PSA ]:
58.20000

[ LogP ]:
1.39880

[ Index of Refraction ]:
1.505

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MU2625500

CHEMICAL NAME :: Hydantoin, 5-methyl-5-phenyl-

CAS REGISTRY NUMBER :: 6843-49-8

LAST UPDATED :: 199706

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C10-H10-N2-O2

MOLECULAR WEIGHT :: 190.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 4,723,1954

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311-H332-H370

[ Precautionary Statements ]:
P260-P280-P301 + P310-P307 + P311

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Selected applications of capillaries with dynamic or permanent anodal electroosmotic flow in chiral separations by capillary electrophoresis.

J. Pharm. Biomed. Anal. 15(9-10) , 1577-84, (1997)

The techniques for a dynamic and permanent reversal of the electroosmotic flow (EOF) were used for the reversal of the enantiomer migration order (EMO) of neutral and cationic analytes in chiral capil...

Synthesis, physicochemical investigation and cytotoxic activity of new Pt(II) complexes with hydantoin ligands.

Eur. J. Med. Chem. 38(6) , 627-32, (2003)

The interaction of cis-dichlorodiaminplatinum(II) (cis-DDP) with 2,4-imidazolidenedione-5-methyl-5-phenyl was studied. The method of preparation of the new Pt(II) complex consisted in precipitation of...