Chamaejasmine

Names

[ Name ]:
Chamaejasmine

[Synonym ]:
(3,3'-Bi-4H-1-benzopyran)-4,4'-dione,2,2',3,3'-tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-,(2R,2'R,3S,3'S)-rel
Chamaejasmine

Biological Activity

[Description]:

Chamaejasmine is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L. Chamaejasmine has antitumor activity. Chamaejasmine induces cell Apoptosis, Autophagy and ROS production, and activates the activity of AMPK/mTOR signal pathway[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Signaling Pathways >> Epigenetics >> AMPK

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

[References]

[1]. Yang D, et al. The role of chamaejasmine in cellular apoptosis and autophagy in MG-63 cells. Biosci Rep. 2019 Jan 15;39(1):BSR20181707.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₂₂O₁₀

[ Molecular Weight ]:
542.49000

[ Exact Mass ]:
542.12100

[ PSA ]:
173.98000

[ LogP ]:
4.48560