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N5-(Diaminomethylene)-2-(difluoromethyl)ornithine

Names

[ CAS No. ]:
69955-43-7

[ Name ]:
N5-(Diaminomethylene)-2-(difluoromethyl)ornithine

[Synonym ]:
Ornithine, N-(diaminomethylene)-2-(difluoromethyl)-
DL-a-(Difluoromethyl)arginine
2-(Difluoromethyl)arginine
DFMA
a-(Difluoromethyl)-DL-arginine
N-(Diaminomethylene)-2-(difluoromethyl)ornithine
a-Difluoromethylarginine

Biological Activity

[Description]:

DL-α-(Difluoromethyl)arginine is an potent, enzyme-activated and irreversible arginine decarboxylases inhibitor. DL-α-(Difluoromethyl)arginine blocks the arginine decarboxylase activity of E.coli and Pseudomonas aeruginosa in vivo[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Kallio A, et, al. DL-alpha-(Difluoromethyl)arginine: a potent enzyme-activated irreversible inhibitor of bacterial decarboxylases. Biochemistry. 1981 May 26;20(11):3163-8.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
445.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H14F2N4O2

[ Molecular Weight ]:
224.21

[ Flash Point ]:
223.5±31.5 °C

[ Exact Mass ]:
224.108475

[ PSA ]:
125.22000

[ LogP ]:
-0.03

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.536

Related Compounds