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4,10-Aromadendranediol

Names

[ CAS No. ]:
70051-38-6

[ Name ]:
4,10-Aromadendranediol

[Synonym ]:
1H-Cycloprop[e]azulene-4,7-diol, decahydro-1,1,4,7-tetramethyl-, (1aR,4R,4aR,7S,7aS,7bR)-
(1aR,4R,4aR,7S,7aS,7bR)-1,1,4,7-Tetramethyldecahydro-1H-cyclopropa[e]azulene-4,7-diol

Biological Activity

[Description]:

Aromadendrane-4β,10α-diol is a sesquiterpene alcohol. Aromadendrane-4β,10α-diol significantly ameliorates the Aβ1-42 peptide-induced memory impairment. Aromadendrane-4β,10α-diol can be used for Alzheimer's disease (AD) research[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Amoah SK, et al. Inhibitory effect of sesquiterpene lactones and the sesquiterpene alcohol aromadendrane-4β,10α-diol on memory impairment in a mouse model of Alzheimer. Eur J Pharmacol. 2015 Dec 15;769:195-202.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
314.4±10.0 °C at 760 mmHg

[ Molecular Formula ]:
C15H26O2

[ Molecular Weight ]:
238.37

[ Flash Point ]:
138.1±13.6 °C

[ Exact Mass ]:
238.193283

[ PSA ]:
40.46000

[ LogP ]:
3.15

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.518

Related Compounds