NCI 240899

Names

[ Name ]:
NCI 240899

[Synonym ]:
True Blue Chloride

Biological Activity

[Description]:

True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[In Vivo]

True Blue can label dorsal root ganglion neurons (DRGNs) and motoneurons (MNs) by soaking the cut sciatic nerve of adult female rats, and does not affect neuronal survival whenever 4 days or 20 weeks after soak[2].

[References]

[1]. M Bentivoglio, et al. Fuorescent retrograde neuronal labeling in rat by means of substances binding specifically to adenine-thymine rich DNA. Neurosci Lett. 1979 May;12(2-3):235-40.

[2]. W T Garrett, et al. Fluoro-Gold's toxicity makes it inferior to True Blue for long-term studies of dorsal root ganglion neurons and motoneurons. Neurosci Lett. 1991 Jul 8;128(1):137-9.

Chemical & Physical Properties

[ Boiling Point ]:
600.6ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₈Cl₂N₄O₂

[ Molecular Weight ]:
417.28900

[ Flash Point ]:
317.1ºC

[ Exact Mass ]:
416.08100

[ PSA ]:
126.02000

[ LogP ]:
7.12160

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
22-24/25