Aramisulpride

Names

[ Name ]:
Aramisulpride

[Synonym ]:
4-Amino-N-{[(2R)-1-ethyl-2-pyrrolidinyl]methyl}-5-(ethylsulfonyl)-2-methoxybenzamide
MFCD04112983
EINECS 275-831-7
B4J10KD2KI
Benzamide, 4-amino-N-[[(2R)-1-ethyl-2-pyrrolidinyl]methyl]-5-(ethylsulfonyl)-2-methoxy-
(R)-amisulpride

Biological Activity

[Description]:

Aramisulpride is a dopamine D2 receptor and serotonin receptor antagonist used for the research of metabolic disorders[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

[References]

[1]. Halse, Reza; Roix, Jeffrey James; Saha, Saurabh.Compositions comprising enantiomers of amisulpride optionally combined with dopamine receptor modulators for treating metabolic disorders.WO2013040164A1

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
558.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₇N₃O₄S

[ Molecular Weight ]:
369.48

[ Flash Point ]:
291.8±30.1 °C

[ Exact Mass ]:
369.172241

[ LogP ]:
1.60

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.546