5(S)-HPETE

Names

[ Name ]:
5(S)-HPETE

[Synonym ]:
6,8,11,14-Eicosatetraenoic acid, 5-hydroperoxy-, (5S,6E,8Z,11Z,14Z)-
(5S,6E,8Z,11Z,14Z)-5-hydroperoxyicosa-6,8,11,14-tetraenoic acid
5(S)-HPETE
5S-HpETE
(5S,6E,8Z,11Z,14Z)-5-Hydroperoxy-6,8,11,14-icosatetraenoic acid
5-Hydroperoxy-6,8,11,14-eicosatetraenoic acid

Biological Activity

[Description]:

5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
518.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₂O₄

[ Molecular Weight ]:
336.466

[ Flash Point ]:
175.6±23.6 °C

[ Exact Mass ]:
336.230072

[ PSA ]:
66.76000

[ LogP ]:
6.38

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.513

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JX3867000

CHEMICAL NAME :: 6,8,11,14-Eicosatetraenoic acid, 5-hydroperoxy-, (S-(E,Z,Z,Z))-

CAS REGISTRY NUMBER :: 71774-08-8

LAST UPDATED :: 199506

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H32-O4

MOLECULAR WEIGHT :: 336.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 50 umol/L

REFERENCE :: DEOND5 Developments in Oncology. (Kluwer Academic Publishers, POB 358, Accord Stn., Hingham, MA 02018-0358) V.1- 1980- Volume(issue)/page/year: 67,73,1991

Safety Information

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
11-36/37/38

[ Safety Phrases ]:
16-26-36

[ RIDADR ]:
UN 1170 3/PG 2

5(S)​-​HPETE