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Biotin-PEG4-acid

Names

[ CAS No. ]:
721431-18-1

[ Name ]:
Biotin-PEG4-acid

[Synonym ]:
Biotin-PEG4-Acid

Biological Activity

[Description]:

Biotin-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H37N3O8S

[ Molecular Weight ]:
491.59900

[ Exact Mass ]:
491.23000

[ PSA ]:
169.75000

[ LogP ]:
1.41800

[ Storage condition ]:
2-8°C


Related Compounds