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CCR8 antagonist 1

Names

[ CAS No. ]:
723304-76-5

[ Name ]:
CCR8 antagonist 1

Biological Activity

[Description]:

CCR8 antagonist 1 (compound 15) is a potente human CCR8 antagonist with a Ki of 1.6 nM[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> CCR

Research Areas >> Infection

Signaling Pathways >> Immunology/Inflammation >> CCR

Research Areas >> Inflammation/Immunology

[Target]

CCR8:1.6 nM (Ki)

[References]

[1]. Jenkins TJ, et al. Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem. 2007;50(3):566-584.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₉N₃O₅S

[ Molecular Weight ]:
495.59

[ Storage condition ]:
-20°C

Related Compounds