Prometryn

Names

[ Name ]:
Prometryn

[Synonym ]:
1,3,5-Triazine-2,4-diamine, N,N'-bis(1-methylethyl)-6-(methylthio)-
N,N'-Diisopropyl-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine
Prometryne
Uvon
6-methylsulfanyl-2-N,4-N-di(propan-2-yl)-1,3,5-triazine-2,4-diamine
N2,N4-diisopropyl-6-methylthio-1,3,5-triazine-2,4-diamine
6-(methylsulfanyl)-N2,N4-di(propan-2-yl)-1,3,5-triazine-2,4-diamine
Primatol Q
N,N'-bis(1-methylethyl)-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine
2-methylmercapto-4,6-diisopropylamino-1,3,5-triazine
EINECS 230-711-3
1,3,5-Triazine-2,4-diamine, N,N-bis(1-methylethyl)-6-(methylthio)-
N,N’-bis(1-methylethyl)-6-(methylthio)-1,3,5-triazine-2,4-diamine
Merin
2-Propanamine, N,N'-[6-(methylthio)-1,3,5-triazine-2,4(1H,3H)-diylidene]bis-
Prometrex
Gesagard
(2Z,4E)-N,N'-Diisopropyl-6-(methylsulfanyl)-1,3,5-triazine-2,4(1H,3H)-diimine
MFCD00055396
Prometryn
Mercazin
Caparol
Selectin

Biological Activity

[Description]:

Prometryn could improves the control of all weed species and increased lint yield compared with the systems[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Dunk Porterfield, et al. Weed management with CGA-362622, fluometuron, and prometryn in cotton. Weed Science, 50(5):642-647 (2002).

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
322.8±25.0 °C at 760 mmHg

[ Melting Point ]:
118-120°C

[ Molecular Formula ]:
C₁₀H₁₉N₅S

[ Molecular Weight ]:
241.356

[ Flash Point ]:
149.0±23.2 °C

[ Exact Mass ]:
241.136108

[ PSA ]:
88.03000

[ LogP ]:
1.91

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.602

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XY4390000

CHEMICAL NAME :: s-Triazine, 2,4-bis(isopropylamino)-6-(methylthio)-

CAS REGISTRY NUMBER :: 7287-19-6

LAST UPDATED :: 199710

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C10-H19-N5-S

MOLECULAR WEIGHT :: 241.40

WISWESSER LINE NOTATION :: T6N CN ENJ BS1 DMY1&1 FMY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2100 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2430 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2138 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - urine volume increased

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >3100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14223 mg/kg/7W-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in adrenal weight Blood - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2400 mg/kg

SEX/DURATION :: female 18-20 day(s) after conception lactating female 2-4 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral Reproductive - Effects on Newborn - physical Reproductive - Effects on Newborn - delayed effects

MUTATION DATA

TYPE OF TEST :: Gene conversion and mitotic recombination

TEST SYSTEM :: Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 500 ug/L

REFERENCE :: CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 21(2),59,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3180 No. of Facilities: 167 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1169 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3180 No. of Facilities: 13 (estimated) No. of Industries: 1 No. of Occupations: 9 No. of Employees: 567 (estimated) No. of Female Employees: 13 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H332-H400

[ Precautionary Statements ]:
P273

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
F,Xn,N

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S26-S36-S61-S60

[ RIDADR ]:
UN 1648 3/PG 2

[ RTECS ]:
XY4390000

[ HS Code ]:
3808931100

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 3808931100

Articles

Assessing the potential for algae and macrophytes to degrade crop protection products in aquatic ecosystems.

Environ. Toxicol. Chem. 30(3) , 622-31, (2011)

Rates of pesticide degradation in aquatic ecosystems often differ between those observed within laboratory studies and field trials. Under field conditions, a number of additional processes may well h...

Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in early life stages of common carp (Cyprinus carpio L.).

Neuro Endocrinol. Lett. 33 Suppl 3 , 130-5, (2012)

The aim of the study was to investigate effects of the triazine herbicide prometryne on early life stages of common carp Cyprinus carpio as indicated by oxidative stress and antioxidant indices.Toxici...

Quantitative analysis of triazine herbicides in environmental samples by using high performance liquid chromatography and diode array detection combined with second-order calibration based on an alternating penalty trilinear decomposition algorithm.

Anal. Chim. Acta 678(1) , 26-33, (2010)

A novel application of second-order calibration method based on an alternating penalty trilinear decomposition (APTLD) algorithm is presented to treat the data from high performance liquid chromatogra...