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BAPTA tetrapotassium salt

Names

[ CAS No. ]:
73630-08-7

[ Name ]:
BAPTA tetrapotassium salt

[Synonym ]:
BAPTAtetrapotassium
BAPTA TETRAPOTASSIUM SALT
Tetrapotassium 2,2',2'',2'''-[1,2-ethanediylbis(oxy-2,1-phenylenenitrilo)]tetraacetate
tetrapotassium 2,2',2'',2'''-[ethane-1,2-diylbis(oxy-2,1-phenylenenitrilo)]tetraacetate
BAPTA POTASSIUM
BAPTA 4K

Biological Activity

[Description]:

BAPTA tetrapotassium is a non-permeable, selective extracellular calcium chelator, with 105-fold greater affinity for Ca2+ than Mg2+. BAPTA tetrapotassium is a valuable tool to study the role of calcium in cell signaling[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

Ca2+ chelator[1]


[References]

[1]. Fredholm BB, et, al. Effect of an intracellular calcium chelator on the regulation of electrically evoked [3H]-noradrenaline release from rat hippocampal slices. Br J Pharmacol. 1993 Jan;108(1):126-31.

[2]. Salinthone S, et, al. Lipoic acid stimulates cAMP production via G protein-coupled receptor-dependent and -independent mechanisms. J Nutr Biochem. 2011 Jul;22(7):681-90.

[3]. Mizutani T, et, al. Sodium Lauryl Sulfate Stimulates the Generation of Reactive Oxygen Species through Interactions with Cell Membranes. J Oleo Sci. 2016 Dec 1;65(12):993-1001.

[4]. Corns LF, et, al. Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells. J Neurosci. 2016 Jan 13;36(2):336-49.

Chemical & Physical Properties

[ Boiling Point ]:
766.6ºC at 760 mmHg

[ Molecular Formula ]:
C22H20K4N2O10

[ Molecular Weight ]:
628.795

[ Flash Point ]:
417.4ºC

[ Exact Mass ]:
627.966614

[ PSA ]:
185.46000

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds