DL-4-Chlorophenylalanine
Names
[ CAS No. ]:
7424-00-2
[ Name ]:
DL-4-Chlorophenylalanine
[Synonym ]:
L-4-Chlorophenylalanine
para-Chlorophenylalanine
2-amino-3-(4-chlorophenyl)propanoic acid
PCP,PCPA
p-Cl-L-Phe-OH
p-Chloro-L-phenylalanine
H-DL-PHE(4-CL)-OH
EINECS 231-051-9
4-Chlorophenylalanine
fenchlonine
RS-4-chlorophenylalanine
DL-Phe(4-Cl)-OH
4-Chloro-phenylalanine
Phenylalanine, 4-chloro-
DL-p-Chlorophenylalanine
4-Chloro-DL-phenylalanine
MFCD00002601
p-Chlorophenylalanine
fenclonin
3-(p-chlorophenyl) alanine
Fenclonine
cp10,188
(2S)-2-amino-3-(4-chlorophenyl)propanoic acid
c-pal
4-Cl-DL-Phe
PCP
(S)-4-Chlorophenylalanine
L-p-Chlorophenylalanine
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
339.5±32.0 °C at 760 mmHg
[ Melting Point ]:
>240 °C (dec.)(lit.)
[ Molecular Formula ]:
C9H10ClNO2
[ Molecular Weight ]:
199.634
[ Flash Point ]:
159.1±25.1 °C
[ Exact Mass ]:
199.040009
[ PSA ]:
63.32000
[ LogP ]:
1.71
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.590
[ Storage condition ]:
−20°C
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY4390010
- CHEMICAL NAME :
- Alanine, 3-(p-chlorophenyl)-, DL-
- CAS REGISTRY NUMBER :
- 7424-00-2
- BEILSTEIN REFERENCE NO. :
- 2805758
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H10-Cl-N-O2
- MOLECULAR WEIGHT :
- 199.65
- WISWESSER LINE NOTATION :
- QVYZ1R DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1794 mg/kg
- SEX/DURATION :
- female 14-19 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- BIMDA2 Biochemical Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 4,516,1970
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H317
[ Precautionary Statements ]:
P280-P301 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R25;R43
[ Safety Phrases ]:
S36/37-S45
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
AY4390010
[ HS Code ]:
2922499990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
Articles
Int. J. Mol. Sci. 16 , 24219-42, (2015)
Plants rich in antioxidant substances may be useful for preventing skin aging. Pomegranates, containing flavonoids and other polyphenolic compounds, are widely consumed due to their beneficial propert...
Chemical genetics reveals a complex functional ground state of neural stem cells.Nat. Chem. Biol. 3(5) , 268-273, (2007)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...
The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.Food Chem. Toxicol. 74 , 28-34, (2014)
The alkenylbenzene methyleugenol occurs naturally in a variety of spices and herbs, including basil, and their essential oils. At high dose levels methyleugenol induces hepatocarcinogenicity in rodent...