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Chikusetsusaponin IV

Names

[ CAS No. ]:
7518-22-1

[ Name ]:
Chikusetsusaponin IV

[Synonym ]:
Araloside A
β-D-glucopyranose, 1-O-[(3β)-3-[(4-O-α-L-arabinofuranosyl-β-D-glucopyranuronosyl)oxy]-28-oxoolean-12-en-28-yl]-
1-O-[(3β)-3-{[4-O-(α-L-arabinofuranosyl)-β-D-glucopyranuronosyl]oxy}-28-oxoolean-12-en-28-yl]-β-D-glucopyranose
chikusetsusaponin IV

Biological Activity

[Description]:

Araloside A (Chikusetsusaponin IV) is a component of Panax japonicus, with low-renin-inhibitory activity, with an IC50 of 77.4 μM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Renin

[Target]

IC50: 77.4 μM (Renin)[1]


[References]

[1]. Takahashi S, et al. Inhibition of human renin activity by saponins. Biomed Res. 2010 Apr;31(2):155-9.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
999.1±65.0 °C at 760 mmHg

[ Melting Point ]:
196-200℃

[ Molecular Formula ]:
C47H74O18

[ Molecular Weight ]:
927.080

[ Flash Point ]:
285.6±27.8 °C

[ Exact Mass ]:
926.487488

[ PSA ]:
291.82000

[ LogP ]:
7.54

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.623

Related Compounds