8-Methylsulfinyloctyl isothiocyanate

Names

[ Name ]:
8-Methylsulfinyloctyl isothiocyanate

[Synonym ]:
8-Methylsulfinyloctyl-isothiocyanat
8-methylsulfinyloctyl isothiocyanate

Biological Activity

[Description]:

8-Methylsulfinyloctyl isothiocyanate, an isothiocyanate, has antimicrobial activity and remarkable inhibitory activity against plant growth[1]. 8-Methylsulfinyloctyl isothiocyanate impair COX-2 mediated inflammatory responses in LPS stimulated raw macrophages[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vitro]

8-methylsulphinyloctyl isothiocyanate (1-10 μM), constituent of watercress, suppresses LPS induced production of nitric oxide and prostaglandin E2 in RAW 264.7 macrophages[2].

[References]

[1]. Jun Kawabata, et al, 8-Methylsulfinyloctyl Isothiocyanate as an Allelochemical Candidate from Rorippa sylvestris Besser, Agricultural and Biological Chemistry, Volume 53, Issue 12, 1 December 1989, Pages 3361–3362.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₉NOS₂

[ Molecular Weight ]:
233.39

[ Exact Mass ]:
233.09100

[ PSA ]:
80.73000

[ LogP ]:
3.67400

[ Storage condition ]:
-20°C

8-Methylsulfinyloctyl isothiocyanate

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Related Compounds